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Image of The Jackson Laboratory for Genomic Medicine illustrates design in service of reduced LPDs. Image: Neoscape

Sustainable design has grown in prominence in recent years as most projects aspire to some level of environmentally conscious design. Research institutions now recognize the significant environmental impacts of their lab facilities, and owners are willing to think creatively to reduce resource utilization, improve interior environments and save capital costs. This climate of mindful resource conservation is an excellent opportunity for designers to leverage their knowledge of constantly evolving sustainable lab design practices to help facilities achieve building performance well beyond code baseline expectations. This article provides 10 practical innovations to help guide decision-making to further elevate sustainable lab design.

1. Reduced lighting power densities (LPD)
Lighting averages 10 to 14% of overall lab energy use. Building codes continually drive down LPD thresholds in specific areas, which can be supplemented by localized task lighting for users and/or tasks requiring greater illumination levels. Further reductions are emerging due to increasing affordability of LEDs for ambient and task lighting, which reduces energy use, particularly cooling loads—the dominant energy use in labs. Combining density reductions with appropriate levels of natural light and illumination controls can provide even more overall energy savings.

Spatial planning is also a critical component in this strategy’s success. Regularly occupied spaces—labs, offices, conference rooms and break rooms—should have access to perimeter glazing to take advantage of natural light, while specialty-use and non-regularly occupied areas should avoid the perimeter. Striking the right balance between access to daylight, controls and efficient fixtures can further reduce LPD without sacrificing visual comfort or draining project budgets.

2. Long-term data management
Computational research is increasingly supplementing, and sometimes replacing, traditional wet-bench-based science. Digital modeling of experiments enables researchers to rapidly test ideas virtually, replicating only the most promising results physically in the wet lab. Facilities are making greater use of on-site data centers to process the massive amount of data generated by these tests. However, this demands a great deal of space, energy for cooling and capital investment in constantly evolving technologies. Cloud computing is the next data management frontier, allowing labs to host minimal on-site data storage while reaping the benefits of limitless capacity, continually updated technology, saved space and reduced utility bills.

3. Cogeneration (co-gen)
Large research facilities with high electrical utility costs and concurrent thermal and electrical demand are benefitting from co-gen. Co-gen typically uses natural gas (and sometimes biomass) as combustion fuel to generate electricity, while capturing waste heat in the form of steam and/or hot water. This can be utilized for building heating, hot water, process demands and even cooling. In regions where fuel is cheap and electricity is expensive, and particularly where incentive programs are available, co-gen can be highly cost effective. It can also be one of the greatest opportunities to reduce a facility’s carbon footprint because grid electricity often results in much higher greenhouse gas emissions. If a lab is located where biomass fuel is readily available, this can be a major step toward becoming carbon-neutral.


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Image of public and lab space at Pfizer Center for Therapeutic Innovation illustrates collaboration, transparency and science on display. Image: John Horner Photography

4. Heat pumps
Heat pumps are available in all shapes and sizes, and are likely effective on any project—regardless of size. Typical boilers maximize efficiency at 95%, but since heat pumps don’t turn fuel into heat, they can achieve 300%, 400%, 500% and higher efficiencies, depending on the system and conditions. Since they run on electricity, heat pumps can be a key net-zero-energy design component when projects also incorporate renewable energy technologies.

5. Resiliency
Resiliency is at the forefront of sustainable facility design due to climate change impacts, such as increased flooding, natural disasters and extreme temperatures. Labs represent a huge capital investment and can exacerbate harm to their surroundings due to the hazardous nature of some experimentation activities. A resilient lab doesn’t look/operate differently from a typical lab; it reflects a philosophy of long-term thinking to ensure the building can maintain operations, structural integrity and safety during the worst possible weather events. For example, placing vital MEP equipment above predicted flood levels increases long-term viability in the event of prolonged flooding. This opens the opportunity for social spaces at grade, which could publicly promote the research conducted and/or serve as public/staff amenities.

Another resilient opportunity is introducing natural ventilation into certain spaces within the lab. 99.9% of the time, this feature can be an employee perk/energy-conservation measure, but during a catastrophic event with prolonged HVAC outages, it could be the means by which the building is ventilated. Resiliency should carry little added cost premium, as it’s less reliant on design features and more indicative of good design. In the future, the level of resilience could determine the insurability of structures located in known areas of risk.

6. Renewables/power purchase agreements (PPA)
The most common building integrated renewables include wind, solar photovoltaics (PV) and solar thermal. PV has become increasingly efficient and affordable due to reduced equipment prices, government incentives and renewable energy credits (RECs). The major hurdle to implementing solar projects extensively has been their initial cost. Conversely, many solar providers offer owners the benefits of their panels in exchange for use of their available space onsite through PPAs. This transferable contract (typically 20 years) ensures energy produced by a provider’s panels will be bought in total by the owner. All first-cost and ongoing maintenance is covered by the provider, whose profitability relies on energy delivery. Eliminating this hurdle means the owner can invest in a slight structural premium to manage the added load and pay off this premium through ongoing energy savings via the fixed energy rate.


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Image of the Univ. of Massachusetts Medical School Biologics Laboratory illustrates concept of planning for big data. Image: Robert Benson Photography

7. Building dashboards/User Interface
There are many approaches to building metering, but it’s crucial to use this information to enhance building performance. Some strategies rely on remote monitoring and algorithms to automatically detect issues and suggest corrective action to facilities staff. Other systems rely on providing immediate graphic feedback to users, educating and engaging them in energy-reduction efforts. These graphic displays can be used in the lab to help change user behaviors. One example is cfm counters that display real-time lab exhaust rates. When fume hood sashes are open, the cfm display goes up. Institutions use this data to hold friendly competitions with incentives for the lab users, encouraging them to close the sash when the fume hoods aren’t in use. Fun, low-cost programs which engage users in a meaningful ways pay huge dividends over a building’s life.

8. Collaboration/Resource sharing
Collaboration is another industry buzzword, which typically focuses on sharing ideas with other research teams within the organization to increase the rate of discovery. Expanding collaboration into resource sharing is a way for institutions to reduce the quantity and cost of lab equipment. Many labs reserve fume hoods similarly to how office personnel reserve conference rooms. When resources are shared, less space is needed—equating to lower operational and maintenance cost. Another hidden savings from higher collaboration is evident when considering time. When successful endeavors are completed in less time and with greater efficiency, the entire institution benefits from greater speed-to-production.

9. Building envelope design/commissioning
As buildings become more efficient and exhaust rates are continually reduced, the building envelope becomes a larger driver of lab energy consumption. Three large holes in typical labs include glazing, infiltration and thermal bridging. The optimal amount of glazing in labs is less than 30% of the wall area. Exceeding 40% significantly increases first-cost and long-term energy cost. To address this issue, infiltration standards have been developed to define building envelope air-tightness testing, such as ASTM E1827 Standard Test Methods for Determining Air-tightness of Buildings Using an Orifice Blower Door. Knowing there will be an air-tightness test often results in contractors achieving very tight envelopes which out-perform the specified maximum infiltration rates.


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Image of Texas A&;M – Qatar illustrates user training prior to ceiling tile and hood fascia panel installation. Image: Erlab

Contemporary energy codes specify “continuous insulation” to address thermal bridging, meaning only fasteners can penetrate the continuous insulation. Most buildings don’t meet code minimum insulation levels due to this common misunderstanding. Several products are available to minimize thermal bridging, such as fiberglass channels, thermally broken brick ties, structural plastic spacers for steel connections and knife-plates to support relieving angles. By specifying these products and contracting proper QA/QC through Building Enclosure Commissioning (BECx) from CDs onward, the gap between predicted and actual energy use will continually narrow.

10. Rethinking lab exhaust & ventilation
The latest trend in net-zero-energy lab design involves synergizing strategies that dramatically reduce exhaust rates and support a healthier indoor environment. Filtered fume hoods capture contaminants within a bank of integrated, top-mounted filters and release the filtered air directly back into the room. While these may not be applicable for all labs, they capture a wide range of chemicals, and are becoming more common and significantly reduce exhaust demand. An added advantage in the remaining exhaust is general room exhaust (not dedicated fume hood exhaust), meaning enthalpy wheels can be used for heat recovery without significant concern about cross-contaminating ventilation air. Since lab air is continually filtered of impurities and chemicals aren’t exhausted into the ambient environment, eliminating re-entrainment of contaminated exhaust, the indoor environmental quality is vastly improved.

Once exhaust rates aren’t driven by fume hoods, the minimum air change rate (ACR) setpoint can be reduced. Air quality monitoring adds an additional layer of safety by detecting fugitive emissions, which activates an alarm and increases exhaust to a higher purge rate. This combination of strategies reduces the typical 6 ACH to 4 ACH, possibly lower. During unoccupied periods, 2 ACH (possibly lower) is acceptable. Since it’s unlikely for multiple labs to experience simultaneous spills, the HVAC system can be designed to purge as few as two zones at once, saving significant first-cost. After this, cooling loads become the primary airflow driver. This remaining demand can be overcome through supplemental hydronic cooling via fan-coil units or fan-coil units serving chilled beams. This results in nearly complete decoupling of ventilation and space-conditioning systems. Overall, this combination of strategies can reduce lab energy consumption less than 50%.

Blake Jackson, AIA, LEED AP (BD+C), is an Associate and the Sustainability Practice Leader at Tsoi/Kobus and Associates. He focuses on integrating sustainable design strategies into projects across all market sectors. Jacob Knowles, LEED AP (BD+C), is the Director of Sustainable Design at BR+A Consulting Engineers where he leads the sustainability and energy team, championing net-zero-energy and best-in-class sustainable design for clients. Stephen Palumbo, AIA, LEED AP (BD+C), is an Associate and Project Manager with Tsoi/Kobus and Associates, and has worked on numerous lab projects with an eye toward cutting-edge solutions for all aspects of lab design.