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Millipore Corp., Bioprocess R&D Center, Billerica, Mass. Design: ARC/Architectural Resources Cambridge. Click to enlarge.

Millipore Corp., Bioprocess R&D Center, Billerica, Mass.

  • Budget: $ 50 million.
  • Size: 110,000 ft2 .
  • Project team: ARC/Architectural Resources Cambridge, Mass., (architecture); Parsons, Boston (MEP engineering); LeMessurier Consultants Inc., Cambridge (structural engineering); BSC Group, Boston (civil engineering); Rolf Jenson & Associates, Framingham, Mass. (FP engineering); McPhail Associates Inc., Cambridge (geotechnical engineering); Levi Wong Design Associates Inc., Cambridge (landscape architecture); Turner Construction Co., Boston (general contractor).
  • Completion date: 3Q2006.
  • Description: Millipore’s Bioprocess division is dedicated to helping pharmaceutical and biotechnology companies to optimize their manufacturing productivity, ensure the quality of drugs, and scale up the production of difficult-to-manufacture biologics. The new facility allows Millipore to develop full-scale applications performance data and processes that simulate commercial conditions, ultimately resulting in increased speed and quality of biopharmaceutical production for their customers. The 110,000-ft2 building contains 47,000 ft2 of lab space and consolidates multiple functions, fostering an even more collaborative approach for the up to 500 professionals who will work there. Millipore chose to build the center in Massachusetts due to its leadership in the biotechnology sector, its talent pool, and its proximity to customers and leading academic institutions.
  • Contact: Karen Gobler, Millipore Corp., 978-763-5294

The Feinstein Institute for Medical Research, North Shore-Long Island Jewish Health System, Manhasset, N.Y.

  • Budget: $45 million
    The Feinstein Institute for Medical Research, North Shore-Long Island Jewish Health System, Manhasset, N.Y. Design: Karlsberger. Click to enlarge.

  • Size: 65,000 ft2
  • Project team: Karlsberger, New York City and Birmingham, Ala. (lab planning, architecture); Lizardos Associates PC, Mineola, N.Y. (MEP engineering); Goldstein Associates, New York City (structural engineering); Feinstein Institute staff (civil and subsurface engineering); Barr & Barr, New York City (construction management).
  • Completion date: 2007.
  • Description: On the Manhasset Campus of North Shore-Long Island Jewish Hospital, one of the nation’s largest private health systems, the new building will expand pharmaceutical testing and other treatment protocols, integrating basic science and clinical research facilities for cancer therapies and rheumatoid arthritis initiatives. The institute occupies an existing 100,000-ft2 laboratory and is one of the nation’s 78 NIH-designated General Clinical Research Centers (GCRC). It is among the top 6% of all NIH-funded institutions across the nation, and is the only research facility on Long Island that is dedicated solely to the study of human disease and the development of treatments and cures. The expansion was made possible by the philanthropy of Leonard and Susan Feinstein, founders of Bed, Bath & Beyond.
  • Contact: Carol Karasek, AIA, Karlsberger, 212-685-2883.

Gordon Scott Hall of Basic Medical Sciences renovation, Wayne State Univ. School of Medicine, Detroit.


  • Budget: $20 million.

  • Size: 40,000-ft2
  • Project team: Lord, Aeck & Sargent, Ann Arbor, Mich. (architecture); Peter Basso Associates, Troy, Mich. (MEP/FP engineering); Robert Darvas Associates, Ann Arbor (structural engineering); L.S. Brinker Co., Detroit (general contractor).
  • Completion date: 3Q2006.
  • Description: Project involved renovating third-floor spaces for research labs, lab support, office, and classroom spaces for the Center for Molecular Medicine & Genetics and the department of pharmacology. Electrical upgrades were made throughout the nine-story building, which is 35 years old. The renovation resulted in an increase of ~20% in usable square footage and allowed previously impractical installations of equipment such as fume hoods, autoclaves, and freezers. The new lab space also allows the School of Medicine to accommodate the work of four additional faculty members.
  • Contact: Rebecca Duffala, Lord, Aeck & Sargent, 404-253-1484.

Cleveland (Ohio) Clinic, Lerner Research Institute, Center for Genomics Research.

  • Budget: $36 million.

  • Size: 151,000 ft2.
  • Project team: Kaczmar Architects Inc., Valley View, Ohio (architecture); Healthspace Design Consultants, Cleveland (lab consultant); Thorson Baker & Associates, Cleveland (MEP/FP engineering); The Ferchill Group, Cleveland (development consultant, construction management); The Krill Co., Cleveland (general contractor).
  • Completion date: 2005.
  • Description: Six-story facility features open, modular labs equipped with mobile carts and tables, expanding the space available to the Lerner Research Institute to 750,00 ft2. Human genomics, stem cell biology, and regenerative medicine programs will be significantly expanded due to the new facilities. About a quarter of the building is devoted to office space. Center is part of the Center for Stem Cell and Regenerative Medicine, a cooperative program involving the Cleveland Clinic as well as Case Western Reserve Univ., the University Hospitals of Cleveland, and Athersys Inc., a local biotech firm.
  • Contact: Chris Kaczmar, Kaczmar Architects, 216-687-1555.

Yale Univ., Lepidopteran Laboratory, New Haven, Conn.

  • Budget: $370,000
  • Size: 1,300 ft2.
  • Project team: Svigals + Partners, New Haven, Conn. (architect); CDA Associates, Norwalk, Conn. (engineer); Fallon Company, North Haven, Conn. (contractor).
  • Completion date: Summer 2006.
  • Description: This project required renovation of an existing carriage house on the Yale Univ. campus to accommodate a lab for genetic research involving butterflies. Special environmental rooms with skylights were provided for raising the butterflies from the larval stage. Other skylit areas allowed the combination of natural and artificial light necessary for butterfly breeding and raising corn plants for food. Also provided were microscopy and support/ office spaces. A custom graphic film sidelight designed by Svigals + Partners features a highly stylized image of the species Bicyclus anynana that is used for the research.
  • Contact: Lisa Keskinen, Svigals + Partners, 203-786-5110.
Univ. of Oklahoma, Biomedical Research Center, Phase II, Oklahoma City. Design: PSA-Dewberry. Photo: Jon B. Petersen/ Jon Petersen Photography. Click to enlarge.

Univ. of Oklahoma, Biomedical Research Center, Phase II, Oklahoma City.

  • Budget: $28.5 million.
  • Size: 122,000 ft2.
  • Project team: PSA-Dewberry, Tulsa, Okla. (prime architect/ engineer, including civil and structural); MBT Architecture (now Perkins +Will), San Francisco (lab consultant); Richard Rietz, Helena, Mont. (programming consultant); Affiliated Engineers, Seattle (MEP engineering); BKI Estimating Consultants, Oklahoma City (cost estimating); The Flintco Cos., Oklahoma City (general contractor).
  • Completion date: 2005.
  • Description: Second phase of biomedical research construction project is a five-floor building containing a full-floor vivarium, 24 research labs, core labs, and associated support. Overhead utility carriers add flexibility to the labs, allowing easy reconfiguration. Other changes made with input from users of Phase 1 included larger tissue culture rooms and more equipment rooms. The research focus includes cancer and genetics.
  • Contact: David L. Huey, AIA, PSA-Dewberry, 918-587-7283.








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